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"In silico"


 From Wikipedia
If the target host* of a phage therapy treatment is not an animal the term "biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy".

In silico
From:"Genomics,Proteomics and Clinical Bacteriology",N.Woodford and Alan P.Johnson

Phrase that emphasizes the fact that many molecular biologists spend increasing amounts of their time in front of a computer screen, generating hypotheses that can subsequently be tested and (hopefully) confirmed in the laboratory.


Phage Therapy is influenced by:

Phage therapy is influenced by:

Country : the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Temporariness
 Mutation rate
Phenotypical delay
Phage cocktail

My point of view

Saturday, 22 May 2010

Alignment with genes or proteins from mycobacterium phages


This is my opinion:
" To distinguish a common point among these phages and their capacity to grow on M.smegmatis and M.ulcerans the Genome alignment of D29, L5 ,Bxz2 and TM4 mycobacterium phages does not provides important information "


By different software the answer is the same!













See Mauve comparison

We obtain something when we compare some proteins or some genes.
Posted by Rodolfo Berretti at 16:04
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