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"In silico"


 From Wikipedia
If the target host* of a phage therapy treatment is not an animal the term "biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy".

In silico
From:"Genomics,Proteomics and Clinical Bacteriology",N.Woodford and Alan P.Johnson

Phrase that emphasizes the fact that many molecular biologists spend increasing amounts of their time in front of a computer screen, generating hypotheses that can subsequently be tested and (hopefully) confirmed in the laboratory.


Phage Therapy is influenced by:

Phage therapy is influenced by:

Country : the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Temporariness
 Mutation rate
Phenotypical delay
Phage cocktail

My point of view

Thursday 29 January 2009

Wound Infections are a good Target




(video phage clinical trial)

From Wound Care Center ( Lubbock, Texas) was easy to collect a lot of information about Bacterial Biofilms and to see the results of Phage Therapy administration on different wounds and venous leg ulcers.

Wound Infection Overview

Investigation of abscesses and deep-seated wound infections
Posted by Rodolfo Berretti at 22:41
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