CDC cholera
From this work:
(December 13, 2010)
Update: Outbreak of Cholera --- Haiti, 2010
Year 2005
"Self-limiting nature of seasonal cholera epidemics:Role of host-mediated amplification of phage"
Phage predation of Vibrio cholerae has recently been reported to be a factor that influences seasonal epidemics of cholera in Bangladesh.....
Year 2006"Modeling the role of bacteriophage in the control of cholera outbreaks"
Year 2008
"Transmission of Vibrio cholerae Is Antagonized by Lytic Phage and Entry into the Aquatic Environment"
Year 2009
From:
"Cholera transmission: the host,pathogen and bacteriophage dynamic"
"For the years of 1928, 1929 and 1934,
totals of 36,000, 130,823 and 871,316 vibriophage doses were prepared and disseminated by the Inquiry staff at the time that outbreaks began in specific study communities in . Vibriophages were also disseminated into community drinking water sources for prophylaxis. The death rates from cholera were compared with control communities for before and after the interventions. The triennial death rates from cholera fell from 30 to 2 per 10,000 in regions that were treated with .
Although these studies had multiple limitations, they do provide the only available data for the efficacy of vibriophage therapy.
Advances in rehydration and antibiotic therapy in the 1930s and 1940s made bacteriophage trials based on mortality end points unethical and statistically challenging."
