"A controlled clinical trial of a therapeutic
bacteriophage preparation in chronic otitis
due to antibiotic-resistant Pseudomonas aeruginosa;a preliminary report of efficacy"
UCL Ear Institute and Royal National Throat, Nose and Ear Hospital, Grays Inn Road, London, and Biocontrol Limited, BioCity, Pennyfoot Street, Nottingham, UK
Clin. Otolaryngol. 2009, 34, 349–357
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjWUFZQhqcteOxfwkwlvOZCypIFvrL5eyl9UNyBMK0KDlJx7Exd5HpqDPJEtl7jP1j2fBtdQY_q5uiYupCl7_DjTSN-9pr5pNmoHMD8ydorJLt7nfqorzsMTdAw-1Q5ySMSZuZ3gj1DGUw/s400/tf5.gif)
The present controlled trial of bacteriophages indicates that this form of biological therapy has considerable promise.
Digital photography before (a) and after (b) in patient A0012.
Patient A0012 had a longstanding resistant otitis externa. There was swelling of the deep canal skin and ulceration in the roof of the canal adjacent to the tympanic membrane. By day 42 this had resolved and the patient was essentially symptom free.