The 10.000 visitors goal is attained.
It is the right moment for rereading a book.
I think it is useful to reread the MARK H.ADAMS' S book: BACTERIOPHAGES, a milestone in bacteriophage research.
From this book:
"Under certain conditions some bacteriophages can attack and kill susceptible bacteria with no evidence of bacterial lysis or of phage multiplication. In these circumstances the phage particle behaves as an antibiotic rather than as a virus."
"Lwoff (1953) lists the characteristic signs of lysogeny as follows:
1. In a lysogenic culture lysogenesis is a property of every cell
and every spore.
2. Bacteria of a lysogenic culture generally can adsorb the mature phage produced by the culture, but are not damaged by it.
3. Lysis of lysogenic bacteria by enzymes, by other phages, or by mechanical means does not liberate mature phage particles.The intracellular phage in lysogenic bacteria is noninfectious;it is prophage.
4. Infection of a susceptible bacterial culture by a temperate phage may result in the conversion of a considerable proportion of the bacterial cells to the lysogenic condition, potentially capable of liberating the same kind of phage that was used to infect them.
5. Lysogenic bacteria can multiply without liberating mature phage and can undergo many cell divisions in the absence of external phage without losing the lysogenic propensity.
6. Lysis of single lysogenic bacterial cells spontaneously or after a characteristic latent period following induction is accompanied by the release of many mature phage particles. Lysogeny is potentially lethal to the bacterial cell."
Worthy of remark
It is important to remember the fundamental principles when we deal with topics in depth regarding Phage therapy .
