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"In silico"


 From Wikipedia
If the target host* of a phage therapy treatment is not an animal the term "biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy".

In silico
From:"Genomics,Proteomics and Clinical Bacteriology",N.Woodford and Alan P.Johnson

Phrase that emphasizes the fact that many molecular biologists spend increasing amounts of their time in front of a computer screen, generating hypotheses that can subsequently be tested and (hopefully) confirmed in the laboratory.


Phage Therapy is influenced by:

Phage therapy is influenced by:

Country : the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Temporariness
 Mutation rate
Phenotypical delay
Phage cocktail

My point of view

Thursday, 14 January 2010

The disassembly of Thermotoga maritima thyX protein




Which is the protein chain of Thermotoga maritima thyX protein that is similar to gp48 D29 mycobacterium phage protein ?

By Discovery Studio 2.5 software(Accelrys) I have disassembled the Thermotoga maritima thyX protein finding 4 chains (A,B,C and D).





Thermotoga maritima thyX protein
without D chain



gp48 D29 mycobacterium phage protein



The D chain could be similar to gp48 D29 mycobacterium phage protein.
Posted by Rodolfo Berretti at 22:05
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