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"In silico"


From Wikipedia
If the target host* of a phage therapy treatment is not an animal the term "biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy".

In silico
From:"Genomics,Proteomics and Clinical Bacteriology",N.Woodford and Alan P.Johnson

Phrase that emphasizes the fact that many molecular biologists spend increasing amounts of their time in front of a computer screen, generating hypotheses that can subsequently be tested and (hopefully) confirmed in the laboratory.


Phage Therapy is influenced by:

Phage therapy is influenced by:

Country : the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Temporariness
Mutation rate
Phenotypical delay
Phage cocktail

My point of view

Sunday, 17 May 2009

Acinetobacter baumannii (MDR), first part


Colonies
are 1 to 2 mm, nonpigmented, domed, and mucoid, with smooth to pitted surfaces.






Acinetobacter baumannii: An Emerging Multidrug-resistant Threat


Wikipedia:Acinetobacter baumannii







Acinetobacter spp.


Acinetobacter


Example of trend in Phage Therapy research

OBJECTIVE: Develop an antibiotic solution or substance consisting of least three different lytic bacteriophages that kill Acinetobacter baumannii for eventual use in human wound infections.




Development of Bacteriophage Therapy for Treatment of A. baumannii Infected Wounds